Nonmetallic Ion Detection with Nanozymes

Most nonmetallic ions such as cyanide ions (CN^-), fluoride (F^-), sulfide anion (S^2-) and pyrophosphate (PPi) do harm to people's health. The determination methods based on nanozymes have the characteristics of portability, speed and high sensitivity, so it has been widely used in practice.

Creative Enzymes develops an advanced platform equipped with advanced instruments and professional staff to detect nonmetallic ion with a high standard. We customize featured services according to the customers' demand. We deliver satisfied and reliable results and reports on time for our customers all over the world.

Detection of Cyanide Ions (CN^-) with Nanozymes

• Cyanide ions (CN^-) are an extremely lethal poison to the human body. Many electrochemical and optical methods have been developed for CN^- detection.
• By using colorimetric and fluorescence methods of organic dyes and nanozymes, Creative Enzymes establishes a technology platform for the detection of CN^-, which has the advantages of high selectivity, sensitivity and simplicity.

Fig. 1 Detection of CN^- ions based on the inhibition of the enzymatic activity of CoO_xH-GO nanozymes.

• The well-dispersed amorphous cobalt hydroxide / oxide modified graphene oxide (CoO_XH-GO), with peroxide-like catalytic activity, can be used for the detection of CN^-.

Detection of Fluoride (F^-) with Nanozymes

• Fluoride ion is a very important anion for many applications, but high concentrations of fluorine are toxic to humans. Therefore, it is important to measure fluoride in various situations.

Fig. 2 Fluoride can boost the activity of nanoceria to oxidize Amplex red producing a fluorescent product.

• Fluorine has many unique chemical properties and it is the element of the highest electronegativity. We provide services to adjust the energy band of the nanozyme by adsorbing or doping highly electron negative F^-.
• It has recently been reported that the oxidase-like activity of CeO₂ nanozymes can be significantly enhanced in the presence of fluoride. Therefore, Creative Enzymes utilizes the enzyme mimicking activity of nanozymes to develop biosensors for the detection of fluoride ions.

Detection of Sulfion Anion (S^2-) with Nanozymes

• Sulfide anion (S^2-) is a common toxic anion. The traditional determination method has high sensitivity, but requires high equipment, reagents as well as the complicated operation.
• Colorimetric methods based on nanozymes are widely used because of their simplicity, visualization, no need for complex equipment, and high detection speed. We establish a colorimetric method for S^2- detection based on Au@MNO2 nanozymes with peroxidase properties.

Detection of Pyrophosphate (PPi) with Nanozymes

• Pyrophosphate (PPi) is one of the most difficult phosphorus sources in industrial wastewater. Because of the coordination ability between pyrophosphate and metal ions, new methods for pyrophosphate detection can be developed.
• We develop a novel colorimetric method for the detection of pyrophosphate, using Lumino-gallium nano assemblies with peroxide-like activity, which is highly sensitive.

Creative Enzymes offers services covering nonmetallic ion detection based on nanozymes to meet your research demands. With years of experience in the biological industry, our professional platforms can help our clients solve various difficulties. If you are interested in our services, please contact us for more details or make an online inquiry.