Enzyme Catalytic Mechanisms

Creative Enzymes is well known for all enzyme studies and provides quality services to support lab research as well as industrial production. Enzymes catalyze all kinds of chemical reactions with high specificity and efficiency. In most cases, enzymes employ cofactors, which are also known as coenzymes or prosthetic groups, to facilitate binding and interacting with the substrate. Therefore, it is important and necessary to study mechanisms in catalytic process.

During the enzyme catalytic process, tiny variation, such as the change of single amino acid, could lead to the huge decrease (increase) of enzyme activity. Therefore, structural analysis is the best way to verify the catalytic mechanism. Creative Enzymes has much experience in structural biology and we have successfully completed many projects. Our advantages are listed below:

• Full range of knowledge and experience
• Supreme technical and equipment platform
• Accurate project evaluation and competitive prices
• Detailed report and timely after-sales service

Based on the strong ability in enzymology, Creative Enzymes offers contract mechanistic studies using multiple technologies including:

• Crystallography (structural biology);
• Site-directed mutagenesis;
• Reporter group labeling of substrate or inhibitor;
• Kinetic measurement with isotope effect, etc.

After identifying the catalytic mechanisms, Creative Enzyme provides further help for enzyme engineering and modification to reach better performance. Please feel free to contact us for more information.