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With the development in extraction methods, more possibilities have been provided to exploration on applications of natural lipids. Natural lipids have potentials in food processing and health products manufacturing. However, the structural diversity is limited in natural lipids, as they are generated by organisms for certain biological functions. Therefore, natural lipids are often chemically modified to provide new properties and functions, thus known as modified lipids or semi-synthetic lipids. Modified lipids are useful tools in research, but limited in pharmaceutical and medical applications due to low thermostability and possible contamination from the animal or plant source. Synthetic lipids are chemically prepared from glycerol. The chemical route leads to even more diverse structures and high purity, which satisfy the special needs in the pharmaceutical industry.