Probiotics. the definition was submitted to many discussions by scientific organizations during the last 30 years, and at the end is live microorganisms that, when administered in adequate amounts, confer a physiological health benefit on the host. However, probiotics have limitations in that they require viability control and have a short shelf life. 

Recently, new definitions have complemented the probiotic area. The term “paraprobiotics” means dead or inactive cells of probiotics that have shown a significant effect on human health. This form of probiotics does not multiply but still has the ability to regulate intestinal flora and enhance immunity.

Paraprobiotics comprise molecules of bacterial cell wall compounds, such as peptidoglycans, teichoic acids, polysaccharides, and cell surface proteins. Paraprobiotics are manufactured by a diverse range of techniques, including thermal treatments, high pressure, ultraviolet rays, sonication, ionizing radiation, and pH modification. Their beneficial health effects include immunomodulatory, intestinal balancing, anticancer, and antimicrobial activities. Moreover, paraprobiotics can exhibit enhanced safety, assure technological and practical benefits and can also be used in products suitable for people with weak immunity and the elderly.

Creative Enzymes provides a variety of Heat-Killed Paraprobiotics for academic and industrial use. Please contact us for product details.