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Native Yeast 6-Phosphogluconic Dehydrogenase
Cat No.
NATE-0009
Description
In enzymology, a phosphogluconate dehydrogenase (decarboxylating) (EC 1.1.1.44) is an enzyme that catalyzes the chemical reaction:6-phospho-D-gluconate + NADP+↔ D-ribulose 5-phosphate + CO2 + NADPH. Thus, the two substRates of this enzyme are 6-phospho-D-gluconate and NADP+, whereas its 3 products are D-ribulose 5-phosphate, CO2, and NADPH. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.
Abbr
6-Phosphogluconic Dehydrogenase, Native (Yeast)
Source
Yeast
Applications
6-phosphoglyconic dehydrogenase (6PGD) is a key enzyme in the oxidative portion of the hexose monophosphate shunt. It is specific for oxidized nicotinamide adenine dinucleotide phosphate (NADP+). 6-phosphogluconate dehydrogenase is involved in the production of ribulose 5-phosphate, which is involved in nucleotide synthesis and the pentose phosphate pathway by generating NADPH. 6-phosphogluconate dehydrogenase is used to study nucleotide synthesis, glucose metabolism, and the protection of cells from oxidative damage.
Form
lyophilized powder.
Enzyme Commission Number
EC 1.1.1.44
Activity
3.0-6.0 units/mg solid
CAS No.
9073-95-4
Unit Definition
One unit will oxidize 1.0 μmole of 6-phospho-D-gluconate to D-ribulose 5-phosphate and CO2 per min at pH 7.4 at 37°C in the presence of NADP+.
Storage
2-8°C
Synonyms
6-Phosphogluconic Dehydrogenase; phosphogluconic acid dehydrogenase; 6-phosphogluconic dehydrogenase; 6-phosphogluconic carboxylase; 6-phosphogluconate dehydrogenase (decarboxylating); 6-phospho-D-gluconate dehydrogenase; EC 1.1.1.44; phosphogluconate dehydrogenase; decarboxylating; 9073-95-4
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Download Datasheet"6-Phosphogluconic Dehydrogenase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1652 | Phosphogluconate dehydrogenase from Human, Recombinant | EC 1.1.1.44 | E. coli | Inquiry | |
| NATE-0796 | 6-Phosphogluconate dehydrogenase from E. coli, Recombinant | EC 1.1.1.44 | 9073-95-4 | E. coli | Inquiry |
| NATE-1937 | 6-Phosphogluconic Dehydrogenase from Microorganism | EC 1.1.1.44 | Microorganism | Inquiry | |
| NATE-0008 | Native Sheep 6-Phosphogluconic Dehydrogenase | EC 1.1.1.44 | 9073-95-4 | Sheep liver | Inquiry |