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Protein Phosphatase-1 Catalytic Subunit, α-Isoform from Human, Recombinant

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Cat No.

NATE-1243

Description

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene. The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbr

PP1CA, Recombinant (Human)

Alias

PP1A; PP1CA

Source

E.coli

Species

Human

Applications

SDS-PAGE; WB; ELISA; IP

Form

Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.

Molecular Weight

41.1kDa

Purity

> 95%

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Synonyms

PPP1CA; protein phosphatase 1; PP-1A; PP1A; PP1alpha; PPP1A

"Protein Phosphatase" Total Products Page

Enzymes

Catalog	Product Name	Source	Price
NATE-0614	Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, Recombinant	E. coli	Inquiry
NATE-0615	Native Rabbit Protein Phosphatase 1C	Rabbit muscle	Inquiry
NATE-0616	Native Bovine Protein Phosphatase 2A1	Bovine	Inquiry
NATE-0617	Native Bovine Protein Phosphatase 2A2	Bovine kidney	Inquiry

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