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Native Bovine Protein Phosphatase 2A1
Cat No.
NATE-0616
Description
Protein Phosphatase 2A1 is a trimer consisting of the A, B, and C subunits of the PP2A family. It has a total molecular weight of 192 kDa. Protein Phosphatase 2A is a cytoplasmic protein, which colocalizes with mictotubule proteins and is involved in the dephosphorylation of the tau protein and oncoprotein 18. Protein Phosphatase 2A1 binds to polymerized microtubule proteins and may be targeted by tubulin in modulating phosphatase activity.
Abbr
PP2A1, Native (Bovine)
Alias
PP2A1; PPA2A1
Source
Bovine
Applications
Protein Phosphatase 2A1 is a divalent cation-dependent protein serine/threonine phosphatase implicated as a growth suppressor and is associated with dis-regulation in cancer. The enzyme is involved in regulating numerous cellular processes and is used to study cell cycle, growth, and differentiation. The protein phosphatase 2A1 has been used to treat human fibroblast cells prior to Western Blot analysis.
Package
vial of 1 μg
Form
Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol
Activity
> 1500 units/mg protein
Purity
>90% (SDS-PAGE)
Unit Definition
One unit will release 1.0 nanomole of phosphate from 32P-labeled phosphorylase A per minute at pH 7.0 at 30°C.
Stability
−70°C
Synonyms
Protein Phosphatase 2A1; PP2A1; PPA2A1
Download
Download Datasheet"Protein Phosphatase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0614 | Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, Recombinant | E. coli | Inquiry | ||
| NATE-0615 | Native Rabbit Protein Phosphatase 1C | Rabbit muscle | Inquiry | ||
| NATE-0617 | Native Bovine Protein Phosphatase 2A2 | Bovine kidney | Inquiry | ||
| NATE-0618 | Native Bovine Protein Phosphatase 2Ac | Bovine kidney | Inquiry |