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Native Bovine Protein Phosphatase 2A1

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Cat No.

NATE-0616

Description

Protein Phosphatase 2A1 is a trimer consisting of the A, B, and C subunits of the PP2A family. It has a total molecular weight of 192 kDa. Protein Phosphatase 2A is a cytoplasmic protein, which colocalizes with mictotubule proteins and is involved in the dephosphorylation of the tau protein and oncoprotein 18. Protein Phosphatase 2A1 binds to polymerized microtubule proteins and may be targeted by tubulin in modulating phosphatase activity.

Abbr

PP2A1, Native (Bovine)

Alias

PP2A1; PPA2A1

Source

Bovine

Applications

Protein Phosphatase 2A1 is a divalent cation-dependent protein serine/threonine phosphatase implicated as a growth suppressor and is associated with dis-regulation in cancer. The enzyme is involved in regulating numerous cellular processes and is used to study cell cycle, growth, and differentiation. The protein phosphatase 2A1 has been used to treat human fibroblast cells prior to Western Blot analysis.

Package

vial of 1 μg

Form

Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol

Activity

> 1500 units/mg protein

Purity

>90% (SDS-PAGE)

Unit Definition

One unit will release 1.0 nanomole of phosphate from 32P-labeled phosphorylase A per minute at pH 7.0 at 30°C.

Stability

−70°C

Synonyms

Protein Phosphatase 2A1; PP2A1; PPA2A1

"Protein Phosphatase" Total Products Page

Enzymes

Catalog	Product Name	Source	Price
NATE-0614	Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, Recombinant	E. coli	Inquiry
NATE-0615	Native Rabbit Protein Phosphatase 1C	Rabbit muscle	Inquiry
NATE-0617	Native Bovine Protein Phosphatase 2A2	Bovine kidney	Inquiry
NATE-0618	Native Bovine Protein Phosphatase 2Ac	Bovine kidney	Inquiry

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