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PDE4D2 active from Human, Recombinant

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Cat No.

NATE-0525

Description

Human PDE4D2 (GenBank Accession No. NM_001197221) amino acids 2-507 (end) with N-terminal GST-tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Abbr

PDE4D, Recombinant (Human)

Alias

PDE4D2; PDE4D

Source

Baculovirus infected Sf9 cells

Species

Human

Applications

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Product Overview

Human PDE4D2 (GenBank Accession No. NM_001197221) amino acids 2-507 (end) with N-terminal GST-tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Form

aqueous solution

Molecular Weight

mol wt 84 kDa

Purity

> 80% (SDS-PAGE)

Unit Definition

One unit is defined as the amount of enzyme that will convert 1 pmole of 3', 5'-cAMP to 5'-AMP per min at 37°C in a reaction buffer.

Storage

−70°C

Pathway

DARPP-32 events, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem

Function

3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-nucleotide phosphodiesterase activity; cAMP binding; drug binding; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity

Synonyms

DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D

"PDE" Total Products Page

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NATE-0511	Native Bothrops atrox Phosphodiesterase I	EC 3.1.4.1	9025-82-5	Bothrops atrox	Inquiry
NATE-0512	Native Crotalus adamanteus venom Phosphodiesterase I	EC 3.1.4.1	9025-82-5	Crotalus adamanteus venom	Inquiry
NATE-0513	Native Crotalus atrox (Western Diamondback Rattlesnake) Phosphodiesterase I	EC 3.1.4.1	9025-82-5	Crotalus atrox (Western Diamondback Rattlesnake)	Inquiry
NATE-0514	Native Bovine Phosphodiesterase 3',5'-Cyclic Nucleotide Activator-deficient	EC 3.1.4.17	9040-59-9	Bovine heart	Inquiry

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