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Native Staphylococcus aureus Sphingomyelinase

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Cat No.

NATE-0673

Description

Sphingomyelin phosphodiesterase is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.

Abbr

SMase, Native (Staphylococcus aureus)

Alias

SMase

Source

Staphylococcus aureus

Form

buffered aqueous glycerol solution; Solution in 50% glycerol containing 0.25 M phosphate buffer, pH 7.5

Enzyme Commission Number

EC 3.1.4.12

Activity

100-300 units/mg protein (Lowry)

CAS No.

9031-54-3

Unit Definition

One unit will hydrolyze 1.0 μmol of TNPAL-sphingomyelin per min at pH 7.4 at 37°C.

Storage

2-8°C

Synonyms

Sphingomyelin phosphodiesterase; EC 3.1.4.12; neutral sphingomyelinase; 9031-54-3; sphingomyelin cholinephosphohydrolase; sphingomyelinase; SMase

"SMase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0672	Native Bacillus cereus Sphingomyelinase	EC 3.1.4.12	9031-54-3	Bacillus cereus	Inquiry
NATE-1160	Native Sphingomyelinase from Streptomyces sp.	EC 3.1.4.12	9031-54-3	Streptomyces sp.	Inquiry
EXWM-3712	sphingomyelin phosphodiesterase	EC 3.1.4.12	9031-54-3		Inquiry