Products

Online Inquiry

Name

Email *

Phone *

Company/Institution

Country or Region

Quantity

Services & Products Interested *

Project Description

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Native Human Cathepsin D

inquiry

Cat No.

NATE-0172

Description

Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced.

Abbr

CTSD, Native (Human)

Alias

CTSD; CPSD

Source

Human liver

Species

Human

Form

lyophilized powder

Enzyme Commission Number

EC 3.4.23.5

Activity

> 250 units/mg protein (E1%/280)

CAS No.

9025-26-7

Unit Definition

One unit will produce an increase in A280 of 1.0 in 30 min at pH 3.3 at 37°C measured as TCA-soluble products using acid-denatured hemoglobin as substrate (1 cm light path).

Storage

−20°C

Pathway

Ceramide signaling pathway, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem

Function

aspartic-type endopeptidase activity; peptidase activity

Synonyms

CTSD; cathepsin D; CLN10; CPSD; HEL-S-130P; EC 3.4.23.5; 9025-26-7

"CTSD" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1707	Cathepsin D from Human, recombinant	EC 3.4.23.5	9025-26-7	E. coli	Inquiry
NATE-1874	Native Human Cathepsin D	EC 3.4.23.5	9025-26-7	Human Spleen	Inquiry
NATE-0171	Native Bovine Cathepsin D	EC 3.4.23.5	9025-26-7	Bovine spleen	Inquiry
EXWM-4287	cathepsin D	EC 3.4.23.5	9025-26-7		Inquiry

+ See More >>