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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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Native Bovine Cathepsin D

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Cat No.

NATE-0171

Description

Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic Human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced.

Abbr

CTSD, Native (Bovine)

Alias

CTSD; CLN10; CPSD

Source

Bovine spleen

Species

Bovine

Form

Lyophilized powder containing Citrate buffer salts

Enzyme Commission Number

EC 3.4.23.5

Activity

> 2.0 units/mg protein

CAS No.

9025-26-7

Molecular Weight

45 kDa

Unit Definition

One unit will produce an increase in A280 of 1.0 per min per mL at pH 3.0 at 37°C measured as TCA-soluble products using hemoglobin as substrate (1 cm light path).

Pathway

Adaptive Immune System, organism-specific biosystem; Collagen degradation, organism-specific biosystem; Lysosome, organism-specific biosystem

Function

aspartic-type endopeptidase activity

Synonyms

CTSD; cathepsin D; 9025-26-7; EC 3.4.23.5; CLN10; CPSD; HEL-S-130P

"CTSD" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1707	Cathepsin D from Human, recombinant	EC 3.4.23.5	9025-26-7	E. coli	Inquiry
NATE-1874	Native Human Cathepsin D	EC 3.4.23.5	9025-26-7	Human Spleen	Inquiry
NATE-0172	Native Human Cathepsin D	EC 3.4.23.5	9025-26-7	Human liver	Inquiry
EXWM-4287	cathepsin D	EC 3.4.23.5	9025-26-7		Inquiry

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