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isocitrate dehydrogenase (NAD+)

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Cat No.

EXWM-0326

Description

Requires Mn2+ or Mg2+ for activity. Unlike EC 1.1.1.42, isocitrate dehydrogenase (NADP+), oxalosuccinate cannot be used as a substrate. In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD+-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP+-linked enzyme that is found in both mitochondria and cytoplasm. The enzyme from some species can also use NADP+ but much more slowly.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 1.1.1.41

CAS No.

9001-58-5

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

isocitric dehydrogenase; β-ketoglutaric-isocitric carboxylase; isocitric acid dehydrogenase; NAD dependent isocitrate dehydrogenase; NAD isocitrate dehydrogenase; NAD-linked isocitrate dehydrogenase; NAD-specific isocitrate dehydrogenase; NAD isocitric dehydrogenase; isocitrate dehydrogenase (NAD); IDH (ambiguous); nicotinamide adenine dinucleotide isocitrate dehydrogenase

Reaction

isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"IDH" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1103	Isocitrate dehydrogenase from Bacillus subtilis, Recombinant	EC 1.1.1.42	9028-48-2	Bacillus subtilis	Inquiry
NATE-1649	Mutant Isocitrate Dehydrogenase 1 R132H from Human, Recombinant			E. coli	Inquiry
NATE-0350	Native Porcine Isocitric Dehydrogenase (NADP)	EC 1.1.1.42	9028-48-2	Porcine heart	Inquiry
NATE-0351	Isocitrate Dehydrogenase (NADP+) from Yeast, Recombinant	EC 1.1.1.42	9028-48-2	Pichia pastoris	Inquiry

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