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Carboxylesterase 1 isoform c from Human, Recombinant
Cat No.
NATE-1916
Description
Carboxylesterase 1 is a member of a large multigene carboxylesterase family. These enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
Source
Baculovirus infected BTI insect cells
Species
Human
Applications
Delivers high catalytic activity, ideal for robust high-throughput screening assays including drug-drug interaction studies, and pharmacokinetic studies for evaluating pro-drugs and non-CYP pathways of elimination.
Form
Liquid
Enzyme Commission Number
EC 3.1.1.1
Activity
≥1000 units/mg protein
CAS No.
9016-18-6
Concentration
5 mg/ml
Unit Definition
One unit will hydrolyze one nanomole of 4-nitrophenyl acetate per minute at pH 7.4 at 37 °C.
Storage
at -70°C
Synonyms
EC 3.1.1.1; Esterase Isoenzyme 1; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase
Download
Download Datasheet"Esterase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1915 | Carboxylesterase 1 isoform b from Human, Recombinant | EC 3.1.1.1 | 9016-18-6 | Baculovirus infected BTI insect cells | Inquiry |
| NATE-1633 | Carboxylesterase 1D from Mouse, Recombinant | Insect cell (Baculovirus) and fused to His-tag at N-terminus | Inquiry | ||
| NATE-0229 | Esterase Isoenzyme 1 from Porcine liver, Recombinant | EC 3.1.1.1 | 9016-18-6 | E. coli | Inquiry |
| NATE-0230 | Esterase Isoenzyme 2 from Porcine liver, Recombinant | EC 3.1.1.1 | 9016-18-6 | E. coli | Inquiry |