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Native Naja mossambica mossambica Phospholipase A2
Cat No.
NATE-0586
Description
Phospholipase A2 (PLA2) hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. It aggressively attacks phospholipids in membranes of intact cells. PLA2 specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
Abbr
PLA2, Native (Naja mossambica mossambica)
Alias
PLA2; PLA2s
Source
Naja mossambica mossambica
Enzyme Commission Number
EC 3.1.1.4
Activity
~1,500 units/mg protein
CAS No.
9001-84-7
Isoelectric point
8.8 (isoenzyme)
Unit Definition
One unit will hydrolyze 1.0 μmole of soybean L-α-phosphatidylcholine to L-α-lysophosphatidylcholine and a fatty acid per min at pH 8.9 at 25°C.
Storage
−20°C
Warnings
The toxic phospholipase A2 from Naja mossambica mossambica. Protein determined by biuret.
Synonyms
Phospholipases A2; EC 3.1.1.4; 9001-84-7; lecithinase A; phosphatidase; phosphatidolipase; phospholipase A; PLA2; Phosphatidylcholine 2-acylhydrolase; PLA2s
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| PLA2-001 | Phospholipase A2 (food grade) | Inquiry | |||
| NATE-0583 | Native Bovine Phospholipase A2 | EC 3.1.1.4 | 9001-84-7 | Bovine pancreas | Inquiry |
| NATE-0589 | PLA2G12A from Human, Recombinant | Mammalian cells | Inquiry | ||
| NATE-0590 | PLA2G12B from Human, Recombinant | Mammalian cells | Inquiry |