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Native Bovine Phospholipase A2

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Cat No.

NATE-0583

Description

Phospholipase A2 (PLA2) hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. It aggressively attacks phospholipids in membranes of intact cells. PLA2 specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.

Abbr

PLA2, Native (Bovine)

Alias

PLA2; PLA2s

Source

Bovine pancreas

Species

Bovine

Form

lyophilized powder; Contains Tris buffer salts.

Enzyme Commission Number

EC 3.1.1.4

Activity

> 20 units/mg protein

CAS No.

9001-84-7

Unit Definition

One unit will hydrolyze 1.0 μmole of soybean L-α-phosphatidylcholine to L-α-lysophosphatidylcholine and a fatty acid per min at pH 8.0 and 37°C.

Storage

−20°C

Warnings

Protein determined by biuret.

Pathway

Acyl chain remodelling of PC, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem

Function

calcium ion binding; phospholipase A2 activity

Synonyms

Phospholipases A2; EC 3.1.1.4; 9001-84-7; lecithinase A; phosphatidase; phosphatidolipase; phospholipase A; PLA2; Phosphatidylcholine 2-acylhydrolase; PLA2s

"PLA2" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
PLA2-001	Phospholipase A2 (food grade)				Inquiry
NATE-0584	Native Crotalus durissus terrificus venom Phospholipase A2	EC 3.1.1.4	9001-84-7	Crotalus durissus terrificus venom	Inquiry
NATE-0585	Native Honey bee venom (Apis mellifera) Phospholipase A2	EC 3.1.1.4	9001-84-7	Honey bee venom (Apis mellifera)	Inquiry
NATE-0586	Native Naja mossambica mossambica Phospholipase A2	EC 3.1.1.4	9001-84-7	Naja mossambica mossambica	Inquiry

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