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Native Bovine Protein Phosphatase 2C
Cat No.
NATE-0619
Description
Protein Phosphatase 2C is a Mg2+-dependent serine/threonine protein phosphatase with a molecular mass of 42–45 kDa, involved in regulating numerous cellular processes. It is ubiquitously expressed and has been isolated from many mammalian tissues including liver, brain, skeletal muscle, retina, and blood platelets. There are two major isotypes associated with this enzyme, 2C1 and 2C2, also known as 2Ca and 2Cb, respectively. Both isozymes appear to be equally Mg2+-dependent and respond similarly to specific substrates. Both are monomers that demonstrate ~75% sequence homology. The molecular masses are similar; 44 kDa and 42 kDa for 2C1 and 2C2, respectively. Additional Type 2C serine/threonine protein phosphatases include 2Cg, 2Cd, Wip1, and NERPP2C, many of which have multiple isozyme members.
Abbr
PP2C, Native (Bovine)
Alias
PP2C
Source
Bovine kidney
Species
Bovine
Package
vial of 1 μg
Form
buffered aqueous glycerol solution
Activity
~1000 units/mg protein
Unit Definition
One unit will release 1.0 nanomole of phosphate from 32P-labeled myelin basic protein at pH 7.0 at 30°C
Stability
−70°C
Buffer
Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol
Synonyms
Protein Phosphatase 2C; PP2C
Download
Download Datasheet"Protein Phosphatase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0614 | Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, Recombinant | E. coli | Inquiry | ||
| NATE-0615 | Native Rabbit Protein Phosphatase 1C | Rabbit muscle | Inquiry | ||
| NATE-0616 | Native Bovine Protein Phosphatase 2A1 | Bovine | Inquiry | ||
| NATE-0617 | Native Bovine Protein Phosphatase 2A2 | Bovine kidney | Inquiry |