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Superoxide Dismutase 2 from Human, Recombinant
Cat No.
NATE-1658
Description
SOD2 is part of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in SOD2 gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. SOD2 destroys radicals which are usually produced within the cells and which are toxic to biological systems.
Abbr
SOD2, Recombinant (Human)
Source
E. coli
Species
Human
Form
Liquid
Enzyme Commission Number
EC 1.15.1.1
Activity
> 1,200 units/mg
Molecular Weight
24.4 kDa (219 aa, 25-222 aa + His Tag)
Purity
> 95% by SDS-PAGE
Unit Definition
One unit will inhibit the rate of reduction of cytochrome c by 50% in a coupled system, using xanthine and xanthine oxidase at pH 7.8 at 25°C in a 1.5 ml reaction volume.
Storage
Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at - 20°C or -70°C. Avoid repeated freezing and thawing cycles.
Synonyms
Superoxide dismutase [Mn]; mitochondrial; IPOB; MNSOD; MVCD6
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1925 | Native Porcine Superoxide Dismutase | EC 1.15.1.1 | 9054-89-1 | Porcine | Inquiry |
| NATE-1868 | Native Roxburgh Superoxide Dismutase | EC 1.15.1.1 | 9054-89-1 | Rosa roxburghii | Inquiry |
| NATE-1910 | Native Bacillus stearothermophilus Superoxide Dismutase | EC 1.15.1.1 | 9054-89-1 | Bacillus stearothermophilus | Inquiry |
| NATE-1659 | Superoxide Dismutase A from Bacterial, Recombinant | EC 1.15.1.1 | E. coli | Inquiry |