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peptidyl-dipeptidase A
Cat No.
EXWM-4053
Description
A Cl--dependent, zinc glycoprotein that is generally membrane-bound. A potent inhibitor is captopril. Important in elevation of blood pressure, through formation of angiotensin II (vasoconstrictor) and destruction of bradykinin (vasodilator). Two molecular forms exist in mammalian tissues, a widely-distributed somatic form of 150- to 180-kDa that contains two non-identical catalytic sites, and a testicular form of 90- to 100-kDa that contains only a single catalytic site. Type example of peptidase family M2
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9015-82-1
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
dipeptidyl carboxypeptidase I; peptidase P; dipeptide hydrolase (ambiguous); peptidyl dipeptidase; angiotensin converting enzyme; kininase II; angiotensin I-converting enzyme; carboxycathepsin; dipeptidyl carboxypeptidase; peptidyl dipeptidase I; peptidyl-dipeptide hydrolase; peptidyldipeptide hydrolase; endothelial cell peptidyl dipeptidase; ACE; peptidyl dipeptidase-4; PDH; peptidyl dipeptide hydrolase; DCP
Reaction
Release of a C-terminal dipeptide, oligopeptide┼Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Download
Download Datasheet"Angiotensin Converting Enzyme" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0014 | Native Porcine Angiotensin Converting Enzyme | EC 3.4.15.1 | 9015-82-1 | Porcine kidney | Inquiry |
| NATE-0015 | Native Rabbit Angiotensin Converting Enzyme | EC 3.4.15.1 | 9015-82-1 | Rabbit lung | Inquiry |
| NATE-0866 | Native Bovine Angiotensin Converting Enzyme | EC 3.4.15.1 | Bovine lung | Inquiry | |
| NATE-0897 | Native Rat Angiotensin Converting Enzyme | EC 3.4.15.1 | 9015-82-1 | Rat lung | Inquiry |