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Native Rabbit Angiotensin Converting Enzyme

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Cat No.

NATE-0015

Description

Angiotensin-converting enzyme (EC 3.4.15.1), or "ACE" indirectly increases blood pressure by causing blood vessels to constrict. It does that by converting angiotensin I to angiotensin II, which constricts the vessels. For this reason, drugs known as ACE inhibitors are used to lower blood pressure. ACE, angiotensin I and angiotensin II are part of the renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. ACE is secreted in the lungs and kidneys by cells in the endothelium (inner layer) of blood vessels.

Abbr

ACE, Native (Rabbit)

Alias

ACE; PDH; DCP

Source

Rabbit lung

Species

Rabbit

Form

lyophilized powder

Enzyme Commission Number

EC 3.4.15.1

Activity

> 2.0 units/mg protein (modified Warburg-Christian)

CAS No.

9015-82-1

Unit Definition

One unit will produce 1.0 μmole of hippuric acid from Hippuryl-His-Leu per min in 50 mM HEPES and 300 mM NaCl at pH 8.3 at 37°C.

Synonyms

ACE; Angiotensin Converting Enzyme; EC 3.4.15.1; dipeptidyl carboxypeptidase I; peptidase P; dipeptide hydrolase, peptidyl dipeptidase; angiotensin converting enzyme; kininase II; angiotensin I-converting enzyme; carboxycathepsin; dipeptidyl carboxypeptidase; "hypertensin converting enzyme" peptidyl dipeptidase I; peptidyl-dipeptide hydrolase; peptidyldipeptide hydrolase; endothelial cell peptidyl dipeptidase; peptidyl dipeptidase-4; PDH; peptidyl dipeptide hydrolase; DCP

"Angiotensin Converting Enzyme" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0014	Native Porcine Angiotensin Converting Enzyme	EC 3.4.15.1	9015-82-1	Porcine kidney	Inquiry
NATE-0866	Native Bovine Angiotensin Converting Enzyme	EC 3.4.15.1		Bovine lung	Inquiry
NATE-0897	Native Rat Angiotensin Converting Enzyme	EC 3.4.15.1	9015-82-1	Rat lung	Inquiry
EXWM-4053	peptidyl-dipeptidase A	EC 3.4.15.1	9015-82-1		Inquiry

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