Description
Galactose-1-phosphate uridyltransferase (GALT) facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.
Abbr
GALT, Native (Galactose-adapted Yeast)
Source
Galactose-adapted yeast
Form
lyophilized powder; Contains buffer salts as Citrate and reduced glutathione
Enzyme Commission Number
EC 2.7.7.12
Activity
20-60 units/mg protein (modified Warburg-Christian)
Unit Definition
One unit will form 1.0 μmole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP+ per min at pH 8.7 at 25°C as detected by a coupled system using phosphoglucomutase.
Synonyms
EC 2.7.7.12; UDP-glucose-hexose-1-phosphate uridylyltransferase; uridyl transferase; hexose-1-phosphate uridylyltransferase; uridyltransferase; hexose 1-phosphate uridyltransferase; UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase; 9016-11-9
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