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Native Bovine Hyaluronidase

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Cat No.

NATE-0347

Description

Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.

Abbr

Hyaluronidase, Native (Bovine)

Source

Bovine testes

Species

Bovine

Form

lyophilized powder

Enzyme Commission Number

EC 3.2.1.35

Activity

Type I, 750-3000 units/mg solid; Type II, 300-1,000 units/mg; Type III, 3,000-15,000 units/mg solid; Type IV, 400-1000 units/mg solid.

CAS No.

37326-33-3

Molecular Weight

mol wt ~55 kDa (four subunits of 14 kDa each)

Unit Definition

One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37°C in a 2.0 ml reaction mixture (45 minute assay).

Storage

−20°C

Pathway

Chondroitin sulfate degradation, organism-specific biosystem; Chondroitin sulfate degradation, conserved biosystem; Defective B4GALT1 causes B4GALT1-CDG (CDG-2d), organism-specific biosystem

Function

hyaluronan synthase activity; hyalurononglucosaminidase activity; transcription factor binding; enzyme binding; hyaluronic acid binding; hyaluronoglucuronidase activity

Synonyms

hyaluronoglucosaminidase; hyaluronidase; hyaluronoglucosidase; chondroitinase; chondroitinase I; hyaluronate 4-glycanohydrolase; EC 3.2.1.35; 37326-33-3

"Hyaluronidase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1923	Recombinant Human Hyaluronidase PH20	EC 3.2.1.35	37326-33-3	CHO	Inquiry
NATE-0348	Native Sheep Hyaluronidase	EC 3.2.1.35	37326-33-3	Sheep testes	Inquiry
NATE-0349	Native Streptomyces hyalurolyticus Hyaluronidase	EC 3.2.1.35	37326-33-3	Streptomyces hyalurolyticus	Inquiry
EXWM-3897	hyaluronoglucosaminidase	EC 3.2.1.35	37326-33-3		Inquiry

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