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N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase
Cat No.
EXWM-2455
Description
Involved in the biosynthesis of chondroitin and dermatan sulfate. The human chondroitin synthetase is a bifunctional glycosyltransferase, which has the 3-β-glucuronosyltransferase and 4-β-N-acetylgalactosaminyltransferase (EC 2.4.1.175) activities required for the synthesis of the chondroitin sulfate disaccharide repeats. Similar chondroitin synthase 'co-polymerases' can be found in Pasteurella multocida and Escherichia coli. There is also another human protein with apparently only the 3-β-glucuronosyltransferase activity.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
269077-98-7
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
chondroitin glucuronyltransferase II; α-D-glucuronate:N-acetyl-β-D-galactosaminyl-(1→4)-β-D-glucuronosyl-proteoglycan 3-β-glucuronosyltransferase
Reaction
UDP-α-D-glucuronate + N-acetyl-β-D-galactosaminyl-(1→4)-β-D-glucuronosyl-proteoglycan = UDP + β-D-glucuronosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-β-D-glucuronosyl-proteoglycan
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Download
Download Datasheet"Chondroitin synthase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1486 | Chondroitin synthase from Pasteurella multocida, Recombinant | EC 2.4.1.226 | 269077-98-7 | E. coli | Inquiry |