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Febuxostat (Uloric)

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Cat No.

CEI-0355

Description

Febuxostat (Uloric)

Alias

Adenuric

CAS No.

144060-53-7

Molecular Weight

316.37

Purity

>99%

Storage

2 years at -20 centigrade

Synonyms

Adenuric

Targets

Molecular Formula

C16H16N2O3S

Solubility

In vitro

Febuxostat displays potent mixed-type inhibition of the activity of purified bovine milk XO, with Ki and Ki values of 0.6 and 3.1 nM respectively. Febuxostat(TMX-67), a newly synthesized xanthine oxidase/xanthine dehydrogenase (XOD/XDH) inhibitor, has almost no effect on DNFB-sensitized mice. At concentrations up to 100 muM, febuxostat has no significant effects on the activities of the following enzymes of purine and pyrimidine metabolism: guanine deaminase, hypoxanthine-guanine phosphoribosyltransferase, purine nucleoside phosphorylase, orotate phosphoribosyltransferase and orotidine-5-monophosphate decarboxylase.

"XDH" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1064	Native Xanthine dehydrogenase from Microorganism	EC 1.17.1.4	9054-84-6	Microorganism	Inquiry
NATE-1065	Native Xanthine Dehydrogenase from Bovine milk	EC 1.17.1.4	9054-84-6	Bovine milk	Inquiry
EXWM-1082	xanthine dehydrogenase	EC 1.17.1.4	9054-84-6		Inquiry