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DNA topoisomerase

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Cat No.

EXWM-5637

Description

These enzymes bring about the conversion of one topological isomer of DNA into another, e.g., the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences, cf. EC 5.99.1.3 DNA topoisomerase (ATP-hydrolysing).

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 5.99.1.2

CAS No.

80449-01-0

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase

Reaction

ATP-independent breakage of single-stranded DNA, followed by passage and rejoining

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"TOPO I" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0707	Native Human Topoisomerase I	EC 5.99.1.2	80449-01-0	Human	Inquiry
NATE-0708	Native Vaccinia virus Topoisomerase I	EC 5.99.1.2	80449-01-0	Vaccinia virus	Inquiry
NATE-0709	Native Wheat germ Topoisomerase I	EC 5.99.1.2	80449-01-0	Wheat germ	Inquiry
NATE-1339	Topoisomerase I from E. coli, Recombinant			E. coli	Inquiry

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