Description
Recombinant Human Acetyl-CoA Carboxylase 2 for advanced research on fatty acid metabolism and enzyme regulation. Perfect for metabolic and biochemical studies. Creative Enzymes delivers high-purity, reliable solutions.
Abbr
ACC2, Recombinant (Human)
Applications
Acetyl-CoA carboxylase is responsible for synthesis of Malonyl-CoA which is an inhibitor of fatty acid oxidation in skeletal muscle mitochondria. The enzyme may be used to study the effect on production of malonyl-CoA as well as fatty acid oxidation during exercise. The enzyme also may be used for ACC regulation study in anti-obesity and anti-type 2 diabetes therapeutics.
Form
Supplied as a solution in 50 mM Tris-HCl, pH 8.0, 275 mM NaCl, 10% glycerol, 1 mM EDTA and 2 mM DTT.
Enzyme Commission Number
EC 6.4.1.2
Activity
> 25 units/μg protein
Unit Definition
One unit will cause the carboxylation of 1 picomole of acetyl-CoA per minute at pH 7.4 at 30 deg C.
Storage
Store at -70°C. Avoid multiple freeze-thaw cycles.
Synonyms
ACACB; ACC2; acetyl-CoA carboxylase beta; acetyl coenzyme A carboxylase; acetyl-CoA carboxylase