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DNA topoisomerase
Cat No.
EXWM-5637
Description
These enzymes bring about the conversion of one topological isomer of DNA into another, e.g., the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences, cf. EC 5.99.1.3 DNA topoisomerase (ATP-hydrolysing).
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
80449-01-0
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase
Reaction
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0707 | Native Human Topoisomerase I | EC 5.99.1.2 | 80449-01-0 | Human | Inquiry |
| NATE-0708 | Native Vaccinia virus Topoisomerase I | EC 5.99.1.2 | 80449-01-0 | Vaccinia virus | Inquiry |
| NATE-0709 | Native Wheat germ Topoisomerase I | EC 5.99.1.2 | 80449-01-0 | Wheat germ | Inquiry |
| NATE-1339 | Topoisomerase I from E. coli, Recombinant | E. coli | Inquiry |