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α(2-3,6,8) Neuraminidase from Clostridium perfringens, Recombinant

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Cat No.

NATE-1277

Description

Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions.

Abbr

α(2-3,6,8) Neuraminidase, Recombinant (Clostridium perfringens)

Source

E. coli

Species

Clostridium perfringens

Product Overview

Neuraminidase is the common name for Acetyl-neuraminyl hydrolase (Sialidase). This Neuraminidase catalyzes the hydrolysis of α2-3, α2-6, and α2-8 linked N-acetyl-neuraminic acid residues from glycoproteins and oligosaccharides.

Form

50 mM NaCl, 20 mM Tris-HCl (pH 7.5 25°C) and 5 mM Na2EDTA.

Activity

~225,000 units/mg

Molecular Weight

43 kDa

Purity

> 95% determined by SDS-PAGE

Concentration

50,000 units/ml

Unit Definition

One unit is defined as the amount of enzyme required to cleave > 95% of the terminal α-Neu5Ac from 1 nmol Neu5Acα2-3Galβ1-3GlcNAcβ1-3Galβ1-4Glc-7-amino-4-methyl-coumarin (AMC), in 5 minutes at 37°C in a total reaction volume of 10 µl.

Storage

at -20°C

Synonyms

neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6

"Neuraminidase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1716	Neuraminidase from Microorganism	EC 3.2.1.18	9001-67-6	Microorganism	Inquiry
NATE-1683	Neuraminidase, recombinant	EC 3.2.1.18	9001-67-6		Inquiry
NATE-0479	Native Clostridium perfringens (C. welchii) Neuraminidase Agarose	EC 3.2.1.18	9001-67-6	Clostridium perfringens (C. welchii)	Inquiry
NATE-0480	Native Clostridium perfringens (C. welchii) Neuraminidase	EC 3.2.1.18		Clostridium perfringens (C. welchii)	Inquiry

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