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α(2-3,6,8) Neuraminidase from Clostridium perfringens, Recombinant
Cat No.
NATE-1277
Description
Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions.
Abbr
α(2-3,6,8) Neuraminidase, Recombinant (Clostridium perfringens)
Source
E. coli
Species
Clostridium perfringens
Product Overview
Neuraminidase is the common name for Acetyl-neuraminyl hydrolase (Sialidase). This Neuraminidase catalyzes the hydrolysis of α2-3, α2-6, and α2-8 linked N-acetyl-neuraminic acid residues from glycoproteins and oligosaccharides.
Form
50 mM NaCl, 20 mM Tris-HCl (pH 7.5 25°C) and 5 mM Na2EDTA.
Activity
~225,000 units/mg
Molecular Weight
43 kDa
Purity
> 95% determined by SDS-PAGE
Concentration
50,000 units/ml
Unit Definition
One unit is defined as the amount of enzyme required to cleave > 95% of the terminal α-Neu5Ac from 1 nmol Neu5Acα2-3Galβ1-3GlcNAcβ1-3Galβ1-4Glc-7-amino-4-methyl-coumarin (AMC), in 5 minutes at 37°C in a total reaction volume of 10 µl.
Storage
at -20°C
Synonyms
neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6
Download
Download Datasheet"Neuraminidase" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1716 | Neuraminidase from Microorganism | EC 3.2.1.18 | 9001-67-6 | Microorganism | Inquiry |
| NATE-1683 | Neuraminidase, recombinant | EC 3.2.1.18 | 9001-67-6 | Inquiry | |
| NATE-0479 | Native Clostridium perfringens (C. welchii) Neuraminidase Agarose | EC 3.2.1.18 | 9001-67-6 | Clostridium perfringens (C. welchii) | Inquiry |
| NATE-0480 | Native Clostridium perfringens (C. welchii) Neuraminidase | EC 3.2.1.18 | Clostridium perfringens (C. welchii) | Inquiry |