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ZM 39923 HCl
Cat No.
CEI-1072
Description
ZM 39923 is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
Abbr
ZM 39923 HCl(JAK1, JAK3, EGFR, TGM2)
Alias
JAK1A, JAK1B, JTK3
CAS No.
1021868-92-7
Molecular Weight
367.91
Purity
0.998
Storage
2 years -20 centigrade Powder 2 weeks4centigradein DMSO 6 months-80centigradein DMSO
Synonyms
JAK1A, JAK1B, JTK3
Targets
JAK1, JAK3, EGFR, TGM2
IC50
4.4nM, 7.1nM, 5.6nM, 10 nM
Molecular Formula
C23H25NO.HCl
Chemical Name
1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-, hydrochloride (1:1)
Solubility
DMSO 30 mg/mL
Water <1 mg/mL
Ethanol 8 mg/mL
Water <1 mg/mL
Ethanol 8 mg/mL
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