Description
A synthetic peptide that irreversibly inhibits activity of DEVD-dependent caspases (e.g., caspase-3 and caspase-7) and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)
Appearance
Crystalline solid
Product Overview
A caspase-3 inhibitor
Synonyms
Z-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)
Molecular Formula
C₃₀H₄₁FN₄O₁₂
Solubility
DMSO (~25 mg/ml) or Ethanol (~ 15 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK
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