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YM201636

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Cat No.

CEI-0094

Description

YM201636 potently inhibits mammalian PIKfyve with an IC50 of 33 nM but not yeast orthologue Fab1 with an IC50 of >5 uM, exhibiting around 100-fold selectivity for PtdIns3P p110-alpha with an IC50 of 3 uM.

CAS No.

371942-69-7

Molecular Weight

467.48

Purity

>99%

Storage

2 years at -20 centigrade

Targets

PI3K

Molecular Formula

C25H21N7O3

Chemical Name

3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3,2:4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-

Solubility

DMSO 35 mg/mL,Water