Description
XL765 is a mixed mTOR/PI3k inhibitor with IC50 of 157, 39, 113, 9 and 43 nM for mTOR, p110α, β, γ and δ, respectively.
Abbr
XL765(MTOR, PIK3CA, PIK3CB, PIK3CG, PIK3CD)
Alias
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Targets
mTOR, p110α, β, γ and δ
IC50
157nM, 39nM, 113nM, 9nM, 43 nM
Molecular Formula
C31H29N5O6S
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL