Description
Chromogenic substrates are peptides that react with proteolytic enzymes under the formation of color. They are made synthetically and are designed to possess a selectivity similar to that of the natural substrate for the enzyme. Attached to the peptide part of the chromogenic substrate is a chemical group which when released after the enzyme cleavage gives rise to color. The color change can be followed spectrophotometrically and is proportional to the proteolytic activity.
Applications
Chromogenic substrate for tPA and broad spectrum of serine esterases, including thrombin and plasmin.
Molecular Weight
504.6 Da
Concentration
about 49.5 µMoles/vial
Stability
Lyophilized product: 30 months at 2-8°C.
Reconstituted product: 7 days at room temperature (18-25°C); 3 months at 2-8 °C. Do not freeze
Synonyms
Chromogenic Substrate for tPA and Broad Spectrum; Chromogenic Substrate; Chromogenic Substrate for tPA; tPA Chromogenic Substrate
Solubility
>= 5 mg/mL in H2O
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