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Topoisomerase I from Mycobacterium tuberculosis, Recombinant
Cat No.
NATE-3205
Description
Topoisomerases are nuclear enzymes that play essential roles in DNA replication, transcription, chromosome segregation, and recombination. All cells have two major forms of topoisomerases: type I, which makes single-stranded cuts in DNA, and type II enzymes, which cut and pass double-stranded DNA. The enzyme is supplied with Assay Buffer (5X concentration) and Dilution Buffer (1X).
Source
E.coli
Species
Mycobacterium tuberculosis
Form
Liquid
Enzyme Commission Number
EC 5.99.1.2
CAS No.
80449-01-0
Unit Definition
1 U of topo I will relax 0.5 µg of supercoiled pBR322 DNA in 30 minutes at 37 °C.
Storage
at -80°C
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