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tissue kallikrein

Cat No.
EXWM-4129
Description
Formed from tissue prokallikrein by activation with trypsin. In peptidase family S1 (trypsin family). A large number of tissue kallikrein-related sequences have been reported for rats and mice, though fewer seem to exist in other mammals. The few that have been isolated and tested on substrates include mouse γ-renin (EC 3.4.21.54), submandibular proteinase A, epidermal growth-factor-binding protein, nerve growth factor γ-subunit, rat tonin, submaxillary proteinases A and B, T-kininogenase, kallikreins k7 and k8 and human prostate-specific antigen (γ-seminoprotein,)
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
389069-73-2
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
glandular kallikrein; pancreatic kallikrein; submandibular kallikrein; submaxillary kallikrein; kidney kallikrein; urinary kallikrein; kallikrein; salivary kallikrein; kininogenin; kininogenase; callicrein; glumorin; padreatin; padutin; kallidinogenase; bradykininogenase; depot-padutin; urokallikrein; dilminal D; onokrein P
Reaction
Preferential cleavage of Arg┼ bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met┼ or Leu┼. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg┼ bonds
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"Kallikrein" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-0143 Native Clostridium histolyticum Clostripain EC 3.4.22.8 9028-00-6 Clostridium histolyticum Inquiry
NATE-0218 Native Mouse Endoproteinase Arg-C EC 3.4.21.35 82047-85-6 Mouse submaxillary gland Inquiry
NATE-0361 Native Human Kallikrein EC 3.4.21.34 9001-01-8 Human plasma Inquiry
NATE-0362 Native Porcine Kallikrein EC 3.4.21.35 9001-01-8 Porcine pancreas Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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