Description
Ticrynafen is a heterocyclic derivative of phenoxyacetic acid which inhibits cytochrome P450 (CYP). Ticrynafen is also a substrate of CYP2C9
Applications
A cytochrome P450 inhibitor.
Synonyms
2-[2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic Acid; [2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic Acid; 2,3-Dichloro-4-(2-thenoyl)phenoxyacetic Acid; 4-(2-Thenoyl)-2,3-dichlorophenoxyacetic Acid; 4-(2-Thienylcarbonyl)-2,3-dichlorophenoxyacetic Acid; ANP 3624; CE 3624; Difluorex; FR 3068; SKF 62698; Selacryn; Thienylic acid; Tienylic Acid
Molecular Formula
C13H8Cl2O4S
Solubility
Soluble in DMSO (~30 mg/ml), ethanol (~30 mg/ml), methanol (~1 mg/ml), and DMF (~30 mg/ml). Insoluble in water at 25 ºC.