Description
The enzyme activity has only been demonstrated in the direction of 5-deiodination. This removal of the 5-iodine, i.e. from the inner ring, largely inactivates the hormone thyroxine.
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
diiodothyronine 5'-deiodinase (ambiguous); iodothyronine 5-deiodinase; iodothyronine inner ring monodeiodinase; type III iodothyronine deiodinase
Reaction
3,3',5'-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + reduced acceptor
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.