Description
Chromogenic substrates are peptides that react with proteolytic enzymes under the formation of color. They are made synthetically and are designed to possess a selectivity similar to that of the natural substrate for the enzyme. Attached to the peptide part of the chromogenic substrate is a chemical group which when released after the enzyme cleavage gives rise to color. The color change can be followed spectrophotometrically and is proportional to the proteolytic activity.
Applications
For research applications.
Chromogenic substrate for Thrombin.
Molecular Weight
552.6 Da (basic structure); 625.6 Da* (*2HCl included)
Concentration
about 45 µMoles/vial
Stability
Lyophilized product: 30 months at 2-8°C.
Reconstituted product: 7 days at room temperature (18-25°C); 3 months at 2-8 °C. Do not freeze
Synonyms
Chromogenic Substrate R2; Chromogenic substrate for Thrombin; Chromogenic substrate; Thrombin Chromogenic substrate
Molecular Formula
C27H36N8O5, 2HCl
Solubility
>= 5 mg/mL in H2O
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