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Thiazovivin

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Cat No.

CEI-0299

Description

Thiazovivin can inhibit ROCK with IC50 of 0.5 uM.

CAS No.

1226056-71-8

Molecular Weight

311.36

Purity

>99%

Storage

2 years at -20centigrade Powder

Targets

ROCK

Molecular Formula

C15H13N5OS

Chemical Name

N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide

Solubility

DMSO 15 mg/mL Water

In vitro

Thiazovivin can inhibit ROCK with IC50 of 0.5 uM. Thiazovivin can enhance the efficiency of fibroblast reprogramming and promote the transformation of fibroblasts into stem cells, when used in combination with SB 431542 and PD 0325901. Thiazovivin can also improve the survival of human embryonic stem cells (hESCs).