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TG-46

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Cat No.

CEI-1117

Description

TG-46 is a JAK inhibitor.

Abbr

TG-46(JAK2, FLT3, RET, JAK3)

Alias

JTK10, THCYT3

Product Overview

JAK inhibitor

CAS No.

936091-15-5

Molecular Weight

510.65

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

JTK10, THCYT3

Targets

JAK2, FLT3, RET, JAK3

IC50

6nM, 25nM, 17nM, 169nM

Molecular Formula

C26H34N6O3S

Chemical Name

N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-pipera zinyl)phenyl]amino]-4-pyrimidinyl]amino]-Benzenesulfonamide

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL