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taxadiene 5α-hydroxylase
Cat No.
EXWM-1048
Description
This microsomal cytochrome-P-450-dependent enzyme is involved in the biosynthesis of the diterpenoid antineoplastic drug Taxol (paclitaxel). The reaction includes rearrangement of the 4(5)-double bond to a 4(20)-double bond, possibly through allylic oxidation.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9035-51-2
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Reaction
taxa-4,11-diene + AH2 + O2 = taxa-4(20),11-dien-5α-ol + A + H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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