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taurochenodeoxycholate 6α-hydroxylase
Cat No.
EXWM-0905
Description
A heme-thiolate protein (P-450). Requires cytochrome b5 for maximal activity. Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on lithocholate and chenodeoxycholate. In adult pig (Sus scrofa), hyocholic acid replaces cholic acid as a primary bile acid.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
105669-85-0
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
CYP3A4; CYP4A21; taurochenodeoxycholate 6α-monooxygenase
Reaction
(1) taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O; (2) lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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