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Takeda-6d
Cat No.
CEI-1148
Description
Takeda-6d showed potent inhibitory activity in both B-RAF with IC50 of 7.0nM and VEGFR2 with IC50 of 2.2nM.
Abbr
Takeda-6d(KDR, SNRPE)
Alias
CD309, FLK1, VEGFR, VEGFR2
CAS No.
1125632-93-0
Molecular Weight
547.99
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
CD309, FLK1, VEGFR, VEGFR2
Targets
VEGFR2, B-RAF
IC50
7.0nM, 2.2nM
Molecular Formula
C27H19ClFN5O3S
Chemical Name
2-chloro-3-(1-cyanocyclopropyl)-N-(5-((2-(cyclopropanecarbox amido)thiazolo[5,4-b]pyridin-5-yl)oxy)-2-fluorophenyl)benzamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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