Description
Takeda-6d showed potent inhibitory activity in both B-RAF with IC50 of 7.0nM and VEGFR2 with IC50 of 2.2nM.
Abbr
Takeda-6d(KDR, SNRPE)
Alias
CD309, FLK1, VEGFR, VEGFR2
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
CD309, FLK1, VEGFR, VEGFR2
Molecular Formula
C27H19ClFN5O3S
Chemical Name
2-chloro-3-(1-cyanocyclopropyl)-N-(5-((2-(cyclopropanecarbox amido)thiazolo[5,4-b]pyridin-5-yl)oxy)-2-fluorophenyl)benzamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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