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Streptokinase from Streptococcus sp., Recombinant

Cat No.
NATE-1630
Description
Streptokinase (SK) is an enzyme secreted by several species of streptococci that can bind and activate human plasminogen. SK is used as an effective and inexpensive thrombolysis medication in some cases of myocardial infarction (heart attack) and pulmonary embolism. Streptokinase belongs to a group of medications known as fibrinolytics, and complexes of streptokinase with human plasminogen can hydrolytically activate other unbound plasminogen by activating through bond cleavage to produce plasmin. There are three domains to Streptokinase, denoted α (residues 1–150), β (residues 151–287), and γ (residues 288–414). Each domain binds plasminogen, although none can activate plasminogen independently.
Source
E.Coli
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Stability
Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Streptokinase should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.
Synonyms
SK; EC 3.4.99.0; 9002-01-1
Solubility
It is recommended to reconstitute the lyophilized Streptokinase in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Formulation
Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4.

"SK" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-0670 Native β-hemolytic Streptococcus Streptokinase EC 3.4.99.0 9002-01-1 β-hemolytic Streptococcus (Lancefield Group C) Inquiry
PHAM-261 Native Streptococcus hemolyticus Streptokinase EC 3.4.99.0 9002-01-1 Streptococcus hemolyticus Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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