Description
Selective inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki = 80 and 15 ng/ml for inhibition of CaM-KKalpha and CaM-KKbeta respectively). Binds to the ATP-binding site. Displays >80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. Cell permeable.
Alias
7-oxo-7H-benzimidazo[2, 1-a]benz[de]isoquinoline-3-carboxylic acid acetate
Product Overview
CAMKK inhibitor
Purity
98% (TLC); NMR (Conforms)
Synonyms
7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate
Molecular Formula
C19H10N2O3 ∙ CH3COOH
Solubility
May be dissolved in: DMSO (10 mg/ml)
Download Datasheet