Description
Staphylokinase (SAK) is a 136-amino acidenzymefrom Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen, which in turn can degrade various host proteins during infection.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Product Overview
Staphylokinase Recombinant produced in E. coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 15.5 kd.The Staphylokinase is purified by proprietary chromatographic techniques.
Molecular Weight
15.5 kDa
Purity
Greater than 97.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Stability
Lyophilized SAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SAK should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Buffer
The protein was lyophilized from a sterile solution containing 20mM phosphate buffer pH-7.
Synonyms
Staphylokinase; SakSTAR; Neutral proteinase; Protease III; SAK