Description
This enzyme plays a central role in a regulatory checkpoint (the σK checkpoint), which coordinates gene expression during the later stages of spore formation in Bacillus subtilis. The enzyme activates proteolytic processing of a sporulation-specific sigma factor, pro-σK, to its mature and active form, σK, by self-cleavage. The enzyme is also subject to secondary proteolysis, which presumably inactivates SpoIVB. The enzyme is also essential for the formation of heat-resistant spores. Belongs in peptidase family S55.
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
sporulation factor IV B protease
Reaction
Self-cleaves Val52┼Asn53, Ala62┼Phe63 and Val74┼Thr75 at the N-terminus of SpoIVB
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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