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Sphingosine Kinase Inhibitor, SKI-II
Cat No.
CEI-0666
Description
Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3-kinase, or PKCα ; at concentrations up to 60 µM.
Appearance
Pale yellow solid
Product Overview
A non-lipid pan-sphingosine kinase (SK) inhibitor
CAS No.
312636-16-1
Molecular Weight
697.99
Purity
>80% by HPLC
Storage
-20 centigrade
Targets
SPHK1
Molecular Formula
C 15 H 11 CIN 2 OS
Chemical Name
4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol
Solubility
DMSO or EtOH
Shipping Conditions
Gel pack
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