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Sphingosine Kinase Inhibitor, SKI-I

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Cat No.

CEI-0667

Description

Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.

Appearance

Off-white solid

Product Overview

A non-lipid sphingosine kinase (SK) inhibitor

CAS No.

306301-68-8

Molecular Weight

306.12

Purity

>98% by NMR

Storage

-20 centigrade

Targets

SPHK1

Molecular Formula

C 25 H 18 N 4 O 2

Chemical Name

5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide

Solubility

DMSO (10 mg/ml) or EtOH (1 mg/ml)

Shipping Conditions

Gel pack