Description
The reaction can occur in both directions. This enzyme occupies a central position in sphingolipid and glycerophospholipid metabolism. Up- and down-regulation of its activity has been linked to mitogenic and pro-apoptotic signalling in a variety of mammalian cell types. Unlike EC 2.7.8.3, ceramide cholinephosphotransferase, CDP-choline cannot replace phosphatidylcholine as the donor of the phosphocholine moiety of sphingomyelin.
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
SM synthase; SMS1; SMS2
Reaction
a ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.