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Smad3 Inhibitor, SIS3
Cat No.
CEI-0657
Description
A potent and selective inhibitor of Smad3 function. SIS3 selectively inhibits TGF-β1/ALK5-induced Smad3 phosphorylation. Also inhibits the TGF-β1 effect on type I procollagen expression at the transcriptional levels via the Smad3-binding site.
Appearance
Pale yellow solid
Product Overview
A Smad3 inhibitor
CAS No.
521984-48-5
Molecular Weight
406.44
Purity
>90% by NMR
Storage
-20 centigrade
Targets
SMAD3
Molecular Formula
C 28 H 27 N 3 O 3 . HCl
Chemical Name
(2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride
Solubility
DMSO
Shipping Conditions
Gel pack
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